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Fully Automated genomic DNA isolation from large volume of blood
Introduction
A very reliable, fully automated, highly reproducible DNA isolation station, to isolate genomic DNA from large volume blood (up to 10 ml). The set up of the platform consists of a Xperimate liquidhandler and one or two Chemagic Separation Module 1’ns of Chemagen. The Xperimate is equipped with 5 ml disposable. The Chemagen MSM1 uses a dispenser to add the reagents to the blood samples and runs the Chemagic DNA Blood Kit.

Features
· Fully automated, no manual interactions
· 5 ml carbon tips (liquid level & clot detection)
· Two configurations; One or two Chemagen MSM1’ns integrated on one Xperimate Liquid handler
· Barcode tracking
· From 1 to 10 ml blood
· Flexispan disposable tip probes
· LIMS connection
· No need to rehydrate your DNA, immediately available
· Isolates up to 192 samples in 8 hours

Gripper for tubes and racks 5 ml tips with liquid level detection
Results
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Volume Blood (ml) |
Average yield [ug] |
Yield *[ug/mL] |
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2 |
56 |
28 |
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5 |
132 |
25 |
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7 |
173 |
24 |
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Table: Yield gDNA from whole blood
*) Concentration measurement on Nanodrop
Top view configuration Xperimate with two Chemagen MSM1’ns |
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This application is a co-development of Synchron Lab Automation, specialists in robotics & engineering, and GC biotech, specialists in Life Sciences & robotics.
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